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General Anesthetics: - Since little is known about the interaction between fluoxetine and general anesthetics, fluoxetine should be discontinued for as long as clinically possible prior to elective su
rgery.
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Warning
Geriatrics: - Elderly patients should initially receive fluoxetine in low dosage with slow progressive increases only if required and tolerated. Patients who have concomitant systemic illnesses or who
are receiving other drugs concomitantly should be under careful observation at all dosage levels.
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Symptoms of overdose may include:
Any medication taken in excess can have serious consequences. An overdose of Prozac can be fatal. In addition, combining Prozac with certain other drugs can cause symptoms of overdose. If you suspect
an overdose, seek medical attention immediately. Common symptoms of Prozac overdose include: Nausea, rapid heartbeat, seizures, sleepiness, vomiting Other symptoms of Prozac ov
erdose include: Coma, delirium, fainting, high fever, irregular heartbeat, low blood pressure, mania, rigid muscles, sweating, stupor
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Adverse Effects
Gastrointestinal: Frequent: Nausea, disturbances of appetite, diarrhea. Infrequent: Vomiting, stomatitis, dysphagia, eructation, esophagitis, gastritis, gingivitis, glossitis, melena, th
irst, abnormal liver function tests. Rare: Bloody diarrhea, hematemesis, gastrointestinal hemorrhage, duodenal ulcer, stomach ulcer, mouth ulceration, hyperchlorhydria, colitis, enteritis, c
holecystitis, cholelithiasis, hepatitis, hepatomegaly, liver tenderness, jaundice, increased salivation, salivary gland enlargement, tongue discoloration, fecal incontinence, pancreatitis.
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Significant Interactions:
When you are taking Prozac, it is especially important that your health care professional know if you are taking any of the following: - Selective serotonin reuptake inhibitors, other (cital
opram [Celexa], fluvoxamine [e.g., Luvox], paroxetine [e.g., Paxil], sertraline [e.g., Zoloft]) or - Street drugs (LSD, MDMA [e.g., ecstasy], marijuana) or - Sumatriptan (e.g., Imitrex) or <
br> - Tramadol (e.g., Ultram) or - Trazodone (e.g., Desyrel) or - Tryptophan or
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In addition, Prozac is used to treat panic disorder, including panic associated with agoraphobia (a severe fear of being in crowds or public places). People with panic disorder usually suffer from pan
ic attacks--feelings of intense fear that develop suddenly, often for no reason. Various symptoms occur during the attacks, including a rapid or pounding heartbeat, chest pain, sweating, trembling, an
d shortness of breath.
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