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How should you take this medication?
Orlistat comes as a capsule to take by mouth. It is usually taken three times a day with each main meal that contains fat. Each time you take orlistat, your meal should contain no more than about 30% of calories from fat. Take orlistat during or up to 1 hour after a meal. If a meal is missed or does not have fat, you may skip your dose. Follow the directions on your prescription label carefully, a nd ask your doctor or pharmacist to explain any part you do not understand.

Orlistat is in a class of drugs called lipase inhibitors. It works in your intestines, where it blocks some of the fat you eat from being absorbed and disgested. This undigested fat is then removed in your bowel movements (BM).

Why is this medication prescribed?
Orlistat is used with a low-calorie diet to help you lose weight and to maintain your weight after weight loss. Orlistat is used in patients with a certain weight who may also have high blood pressure , diabetes, high cholesterol, or heart disease.

- Orlistat is in a class of drugs called lipase inhibitors. It works in your intestines, where it blocks some of the fat you eat from being abs orbed and disgested. This undigested fat is then removed in your bowel movements (BM).

Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to c hange the dose, or other precautions may be necessary. When you are taking orlistat, it is especially important that your health care professional know if you are taking the following:

- Warf arin¡XOrlistat may decrease the absorption of vitamin K and may change your bleeding time

Cautions
Follow the diet program your doctor has given you. You should evenly divide your daily intake of fat, carbohydrates, and protein over three main meals. If orlistat is taken with a meal very high in fa t (30% total daily calories from fat), you may experience more side effects from the medication.

Orlistat blocks your body's uptake of some fat-soluble vitamins and beta carotene. Therefore, when you use orlistat you should take a daily multivitamin supplement that contains vitamins A, E, K, and beta-carotene. Take the vitamin once a day, 2 hours before or 2 hours after taking orlistat, o r take the vitamin at bedtime.

What side effects may occur?
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor as soon as possible if any of the following side effects occur:

- Bodyache; chills; cough; fever; headache; nasal congestion; runny nose; sneezing; sore throat

- Tightness in chest; tooth or gum problems ; troubled breathing; wheezing

- Bloody or cloudy urine; change in hearing ; contagious diarrhea; difficult or painful urination; earache; frequent ur ge to urinate; pain in ear

What special precautions should I follow?
Before taking orlistat,

tell your doctor and pharmacist if you are allergic to orlistat or any other drugs.
tell your doctor if you have or have ever had anorexia nervosa or bulimia, gal lstones, thyroid disease, diabetes, kidney problems, or if you consistently have problems absorbing food (malabsorption syndrome).
tell your doctor if you are pregnant, plan to become pregnant, o r are breast-feeding.




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