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Precautions while Using this Medicine
Before you have any medical tests, tell the person in charge that you are taking this medicine. Caffeine (present in some butalbital and acetaminophen combinations) interferes with the results of cert ain tests that use dipyridamole (e.g., Persantine) to help show how well blood is flowing to your heart. Caffeine should not be taken for 8 to 12 hours before the test. The results of other tests may also be affected by butalbital and acetaminophen combinations.

Other medical problems
PregnancyˇX

- For butalbital: Barbiturates such as butalbital have been shown to increase the chance of birth defects in humans. Also, one study in humans has suggested that barbiturates tak n during pregnancy may increase the chance of brain tumors in the baby.Butalbital may cause breathing problems in the newborn baby if taken just before or during delivery.
- For acetaminophen: Al though studies on birth defects with acetaminophen have not been done in pregnant women, it has not been reported to cause birth defects or other problems.
- For caffeine: Use of large amounts of caffeine during pregnancy may cause problems with the heart rhythm and the growth of the fetus.

Symptoms of overdose may include:
Seek emergency medical attention. Symptoms of an acetaminophen / butalbital / caffeine - Fioricet overdose include insomnia, restlessness, tremor, nausea, vomiting, diarrhea, abdominal pain, sweating, seizures, drowsiness, decreased breathing,

Proper Use of This Medicine
The combination of acetaminophen, butalbital, and caffeine comes as a capsule and tablet to take by mouth. It usually is taken every 4 hours as needed. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take acetaminophen, butalbital, and caffeine exactly as directed. Do not take more than six tablets or capsules in 1 day. If you think that you need more to relieve your symptoms, call your doctor.

This medication can be habit-forming. Do not take a larger dose, take it more often, or for a longer per iod than your doctor tells you to.

Possible Side Effect
Check with your doctor immediately if any of the following side effects occur, especially if several of them occur together:

Bleeding or crusting sores on lips; chest pain; fever with or wi thout chills; hive-like swellings (large) on eyelids, face, lips, and/or tongue ; muscle cramps or pain; red, thickened, or scaly skin; shortness of breath, troubled breathing, tightness in chest, or wheezing; skin rash, itching, or hives; sores, ulcers, or white spots in mouth (painful); sore throat

Other Medicines
When you are taking a butalbital and acetaminophen combination, it is especially important that your health care professional know if you are taking any of the following:

- Anticoagulants (b lood thinners), or
- Carbamazepine (e.g., Tegretol) or
- Contraceptives, oral (birth control pills) containing estrogen, or
- Corticosteroids (cortisone-like medicines) or
- Cortic otropin (e.g., ACTH)ˇXButalbital may make these medicines less effective




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