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Precautions while Using this Medicine
If you are taking antacids, cimetidine (e.g., Tagamet), famotidine (e.g., Pepcid), nizatidine (e.g., Axid), omeprazole (e.g., Prilosec), or ranitidine (e.g., Zantac) while you are taking itraconazole or ketoconazole, take the other medicine at least 2 hours after you take itraconazole or ketoconazole . If you take these medicines at the same time that you take itraconazole or ketoconazole, they wi ll keep your antifungal medicine from working properly.

Overdosage
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical treatment immediately.

Symptoms of Diflucan overdose may include:
- Hallucinations , paranoia

What special precautions should I follow?
Older adults¡XMany medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause differ nt side effects or problems in older people. There is no specific information comparing use of Diflucan in the elderly with use in other age groups

Possible food and drug interactions when taking this medication
When you are taking Diflucan, it is especially important that your health care professional know if you are taking any of the following:

- Vincristine (e.g., Oncovin)¡XMetabolism of these dr gs may be delayed by itraconazole.
- Felodipine (e.g., Plendil) or
- Nifedipine (e.g., Procardia) or
- Verapamil (e.g., Isoptin, Covera)¡XConcurrent use can cause water retention or sl the heart rate.
- Carbamazepine (e.g., Tegretol) or
- Phenobarbital (e.g., Luminal)
- Phenytoin (e.g., Dilantin)¡XConcurrent use with itraconazole may decrease itraconazole concentrati ns. Phenytoin concentrations may be increased.
- Cyclosporine (e.g., Sandimmune, Neoral)

What side effects may occur?
Although side effects from fluconazole are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

- upset stomach
- loss of appetite
- altered taste
- diarrhea or loose stools
- headache
- dizziness
- fatigue

If you experience any of the following symptoms, call your doctor immediately:

- rash
- itching
- vomiting
- yellowing of the skin or eyes
- dark urine
- pale stools

What is this medicine
Diflucan is used to treat fungal infections called candidiasis (also known as thrush or yeast infections). These include vaginal infections, throat infections, and fungal infections elsewhere in the b ody, such as infections of the urinary tract, peritonitis (inflammation of the lining of the abdomen), and pneumonia. Diflucan is also prescribed to guard against candidiasis in some people receiving bone marrow transplants, and is used to treat meningitis (brain or spinal cord inflammation) caused by another type of fungus.

In addition, Diflucan is now being prescribed for fungal infect ions in kidney and liver transplant patients, and fungal infections in patients with AIDS.




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